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Updated: Feb 12, 2026
09:29
Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
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[Autoantibodies in Neuromyelitis Optica Spectrum Disorders]
Ichiro Nakashima1, Tetsuya Akaishi
1Department of Neurology, Tohoku Medical and Pharmaceutical University.
Brain and Nerve = Shinkei Kenkyu No Shinpo
|April 11, 2018
Abstract:
Neuromyelitis optica was previously considered a subtype of multiple sclerosis until a specific serum antibody, NMO-IgG, was discovered in 2004. In 2012, anti-MOG antibody was found specifically in the serum of patients whose presentation was similar to those with neuromyelitis optica. These autoantibodies are pathogenic and are important disease markers when reaching a diagnosis.
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