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Updated: Feb 12, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
Published on: April 12, 2024
Management of Craniopharyngioma - Perspectives beyond Surgery and Endocrinology
Rachel K Crowley1,2, Christopher J Thompson3
1Consultant Endocrinologist, St Vincent's University Hospital, Elm Park, Dublin, Ireland.
Abstract:
The excess mortality in craniopharyngiomas is attributable to their size, site and the traditional surgical approach; aggressive resection predisposes to hypothalamic complications such as obesity, somnolence, thirst disorders and neurocognitive dysfunction. Recently, treatment has been modified to partial resection and radiotherapy. The role of the endocrinologist has expanded from identification and replacement of hormone deficits to include management of hypothalamic disease. Future treatment of craniopharyngioma with neo-adjuvant chemotherapy to minimise surgical resection may improve the outcomes for these patients.
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