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Updated: Feb 12, 2026
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Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
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De novo overactive bladder after robot-assisted laparoscopic radical prostatectomy
Yoshihisa Matsukawa1, Yashushi Yoshino1, Shohei Ishida1
1Department of Urology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Neurourology and Urodynamics
|April 11, 2018
Summary
Robot-assisted radical prostatectomy (RARP) can lead to de novo overactive bladder (OAB) in about 40% of patients. Decreased urethral function is a significant factor contributing to this post-surgical OAB.
Area of Science:
- Urology
- Surgical Oncology
- Continence Medicine
Background:
- Robot-assisted laparoscopic radical prostatectomy (RARP) is a common treatment for localized prostate cancer.
- Storage symptoms, particularly de novo overactive bladder (OAB), can significantly impact quality of life after RARP.
Purpose of the Study:
- To investigate the incidence of de novo OAB following RARP.
- To identify factors associated with the development of de novo OAB after RARP.
Main Methods:
- Prospective study of 245 patients without pre-existing OAB undergoing RARP.
- Evaluation of lower urinary tract symptoms (subjective and objective) pre- and post-surgery.
- Comparison of operative and urodynamic parameters between patients with and without de novo OAB at 3 months post-RARP.
Main Results:
- De novo OAB occurred in 37.8% of patients post-RARP.
- Patients with de novo OAB showed significantly lower post-operative continence rates (8.0% vs. 79.7%).
- Pre-operative IPSS-QOL score and post-operative maximum urethral closing pressure (MUCP) were significant predictors of de novo OAB.
Conclusions:
- The incidence of de novo OAB after RARP is substantial (approx. 40%).
- Impaired urethral function, indicated by reduced MUCP, is significantly associated with de novo OAB development post-RARP.
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