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Updated: Feb 12, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
Published on: March 17, 2023
Recent advances in managing tricuspid regurgitation
Benedetto Del Forno1, Elisabetta Lapenna1, Malcom Dalrymple-Hay2
1IRCCS San Raffaele Hospital, Milan, Italy.
Trans-catheter tricuspid valve interventions offer a promising alternative to surgery for severe tricuspid regurgitation. Current options show feasibility but require further clinical evaluation due to technical challenges.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Isolated tricuspid valve surgery presents high morbidity and mortality risks.
- Severe tricuspid regurgitation poses significant clinical challenges.
- Trans-catheter interventions are emerging as alternatives to surgical repair.
Purpose of the Study:
- To review current trans-catheter treatment options for severe tricuspid regurgitation.
- To discuss the feasibility and challenges of these novel interventions.
Main Methods:
- Review of currently available trans-catheter devices for tricuspid valve intervention.
- Analysis of implantation locations and preliminary clinical data.
Main Results:
- Feasibility of trans-catheter tricuspid valve interventions has been demonstrated.
- Various devices are available for implantation in different tricuspid valve locations.
- Clinical experience is preliminary, with ongoing technical and clinical challenges.
Conclusions:
- Trans-catheter tricuspid valve interventions are an evolving alternative for severe tricuspid regurgitation.
- Further clinical experience and device refinement are necessary.
- These minimally invasive approaches may reduce surgical risks for select patients.
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