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Related Concept Videos

Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

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Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
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Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

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Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
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Smooth Endoplasmic Reticulum01:21

Smooth Endoplasmic Reticulum

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Smooth endoplasmic reticulum or smooth ER is a sub-organelle with specialized functions in animal cells and plant cells. It is often associated with the tubule morphology of the endoplasmic reticulum.
The ER provides optimal conditions for synthesizing steroid hormones and lipids, such as phospholipids and triglycerides. Traditionally, lipid metabolism was considered to be a smooth ER function. However, there is no direct evidence to prove that rough ER is completely excluded from lipid...
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Functions of Smooth Muscles01:23

Functions of Smooth Muscles

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Smooth muscles are an important type of muscle tissue that plays a vital role in the involuntary movements of internal organs. For example, they help regulate the movement of food through the gut and the flow of blood through the circulatory system.
Function of visceral smooth muscles
Visceral smooth muscle is found in the walls of all hollow organs, except the heart, and is a key player in the involuntary movements that drive the functioning of these internal organs. This tissue is arranged in...
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Smooth Muscle Contraction01:25

Smooth Muscle Contraction

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Smooth muscle contraction is a complex process vital for various bodily functions, from maintaining blood vessel tension to facilitating the movement of food through the digestive tract. Unlike striated muscles, smooth muscle contraction begins more slowly and lasts longer.
The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...
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Related Experiment Video

Updated: Feb 12, 2026

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
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A Smooth Esophageal Stricture Causing Dysphagia.

Edoardo Forti1, Giulia Bonato2,3, Lorenzo Dioscoridi1

  • 1Digestive and Interventional Endoscopy Unit, ASST Grande Ospedale Metropolitano Niguarda, Piazza dell'Ospedale Maggiore 3, 20162, Milan, Italy.

Dysphagia
|April 12, 2018
PubMed
Summary
This summary is machine-generated.

Metastasis from lung cancer to the esophagus is rare. An echobronchoscope (EBUS) was crucial for diagnosing esophageal narrowing caused by pulmonary adenocarcinoma metastasis.

Keywords:
EndoultrasonographyEsophageal stenosisEsophageal strictureFine-needle aspirationLung cancerMetastasis

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Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
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Area of Science:

  • Gastroenterology
  • Pulmonology
  • Oncology

Background:

  • Esophageal dysphagia in lung cancer patients typically results from direct tumor invasion or nodal spread.
  • Metastatic spread from distant lung neoplasms to the esophagus is infrequently documented.

Observation:

  • A case presented with smooth esophageal narrowing due to intramural metastasis from pulmonary adenocarcinoma.
  • The patient had no prior history of cancer, making the diagnosis challenging.

Findings:

  • A standard linear echoendoscope was unable to traverse the malignant esophageal stricture.
  • Fine-needle aspiration biopsy using an echobronchoscope (EBUS) successfully obtained a histological diagnosis.

Implications:

  • Echobronchoscopy (EBUS) is a valuable tool for diagnosing esophageal strictures of unclear etiology.
  • This case highlights the importance of considering rare metastatic patterns in lung cancer patients presenting with dysphagia.