Related Experiment Video

Updated: Feb 12, 2026

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
12:00

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

10.7K

Nipah Virus Infection

Brenda S P Ang1,2,3, Tchoyoson C C Lim4,5, Linfa Wang6,7

  • 1Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore Brenda_Ang@ttsh.com.sg.

Journal of Clinical Microbiology
|April 13, 2018
PubMed

Insights

Nipah virus, a bat-borne paramyxovirus, causes severe disease in humans and animals. Outbreaks in Asia highlight varied transmission routes and the urgent need for therapeutics.

Area of Science:

  • Virology
  • Zoonotic Diseases
  • Epidemiology

Background:

  • Nipah virus (NiV) is a zoonotic paramyxovirus first identified in Malaysia in 1998.
  • It is closely related to Hendra virus, also known for causing severe illness.

Observation:

  • Clinical manifestations of NiV infection range from asymptomatic cases to fatal encephalitis.
  • Since 1999, Malaysia has reported no further cases, but outbreaks persist in Bangladesh and India.
  • Transmission dynamics differ geographically: pig contact in Malaysia vs. date palm sap ingestion and human-to-human spread in Bangladesh and India.

Findings:

  • Bats serve as the primary reservoir for Nipah virus.
  • The virus poses a significant threat to both human and animal health.

Implications:

  • Current management relies on supportive care and prevention due to the absence of effective therapeutics.
  • Understanding distinct transmission patterns is crucial for targeted public health interventions in affected regions.
  • Further research into NiV pathogenesis and antiviral strategies is warranted to combat future outbreaks.
Keywords:
Nipahencephalitisoutbreaks

More Related Videos

Establishment of Viral Infection and Analysis of Host-Virus Interaction in Drosophila Melanogaster09:57

Establishment of Viral Infection and Analysis of Host-Virus Interaction in Drosophila Melanogaster

Published on: March 14, 2019

11.4K
Ex Vivo Infection of Live Tissue with Oncolytic Viruses12:08

Ex Vivo Infection of Live Tissue with Oncolytic Viruses

Published on: June 25, 2011

13.4K

Related Concept Videos

What are Viruses?00:50

What are Viruses?

Overview
128.4K
Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
12.8K
Introduction to Virus01:28

Introduction to Virus

Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
1.8K
Viruses of Archaea01:29

Viruses of Archaea

Archaeal viruses play a crucial role in the ecosystems of extremophilic archaea, particularly those belonging to the phyla Euryarchaeota and Crenarchaeota. By shaping host evolution and facilitating gene transfer, these viruses influence microbial communities and contribute to genetic diversity in extreme environments. The archaea they infect thrive in acidic hot springs and hydrothermal vents characterized by high temperatures and low pH. Archaeal viruses exhibit remarkable structural...
525
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
952
Stages of Infection01:26

Stages of Infection

Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
65.5K