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Nonvenereal Penile Dermatoses: A Retrospective Study.
Ana Marcos-Pinto1, Luís Soares-de-Almeida1,2, João Borges-Costa1,2,3
1University Clinic of Dermatology, Hospital de Santa Maria, Lisbon, Portugal.
This study found inflammatory diseases are the most common nonvenereal penile dermatoses, with Zoon balanitis being most frequent. Squamous cell carcinoma (SCC) was the most common malignancy, highlighting the need for accurate diagnosis of penile conditions.
Area of Science:
- Dermatology
- Pathology
- Urology
Background:
- Nonvenereal diseases affecting the penis can significantly impact quality of life.
- Clinical presentation of penile dermatoses is often similar, necessitating histological examination for accurate diagnosis.
Purpose of the Study:
- To characterize nonvenereal penile dermatoses with histological confirmation.
- To analyze the prevalence of inflammatory and neoplastic conditions affecting the penis over a 9-year period.
Main Methods:
- Retrospective review of all penile biopsies performed between January 1, 2007, and December 31, 2015.
- Analysis of patient demographics and identified dermatoses, categorizing them into inflammatory and neoplastic groups.
Main Results:
- A total of 108 patients were included, with 18 different dermatoses identified.
- Inflammatory diseases (65.7%) were more common than neoplastic diseases (34.3%).
- Most frequent inflammatory conditions included Zoon balanitis (27.8%), lichen sclerosus (15.7%), and psoriasis (11.1%). Squamous cell carcinoma (SCC) was the most common malignancy (15.7%), and erythroplasia of Queyrat the most common in-situ tumor (8.3%).
Conclusions:
- Inflammatory dermatoses are the most frequent diagnoses in penile biopsies.
- Squamous cell carcinoma (SCC) is the predominant malignant tumor found in penile biopsies.
- Psoriasis and lichen planus often present with isolated penile lesions.
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