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INVASIVE SALMONELLOSIS PRESENTING AS A LUNG ABSCESS: A CASE REPORT
Summary
Salmonella species, an uncommon cause of lung abscess, can affect immunocompromised individuals. This case highlights successful antibiotic treatment for a Salmonella-induced lung abscess in a patient with diabetes and glomerulonephritis.
Area of Science:
- Infectious Diseases
- Pulmonology
- Immunology
Background:
- Salmonella species are typically associated with gastrointestinal infections.
- Lung abscesses are uncommon manifestations of Salmonella infections.
- Immunocompromised status, such as that induced by corticosteroid therapy for focal segmental glomerulosclerosis and diabetes mellitus, increases susceptibility to invasive Salmonella infections.
Purpose of the Study:
- To report a rare case of Salmonella-induced lung abscess.
- To emphasize the importance of considering Salmonella in the differential diagnosis of lung abscesses, particularly in immunocompromised patients.
- To illustrate a successful conservative management approach.
Main Methods:
- A 59-year-old male with a history of type 2 diabetes mellitus and focal segmental glomerulosclerosis on prednisolone presented with symptoms of lung abscess.
- Diagnostic workup included chest X-ray and computed tomography (CT) of the lung, revealing cavitary lesions.
- Sputum culture identified Salmonella species group B.
Main Results:
- The patient presented with persistent cough, fever, and findings consistent with a cavitary lung lesion on imaging.
- Sputum culture confirmed Salmonella species group B as the causative agent.
- Intravenous ceftriaxone followed by oral cefdinir resulted in successful treatment and significant radiological improvement without surgical intervention.
Conclusions:
- Salmonella species can cause lung abscesses, especially in immunocompromised individuals.
- Prompt diagnosis and appropriate antibiotic therapy are crucial for managing Salmonella-induced lung abscesses.
- Conservative management, including antibiotics alone, can be effective in select cases, avoiding the need for surgical drainage.
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