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Updated: Feb 12, 2026

Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts
Published on: August 7, 2018
Photo-induced anticancer activity and singlet oxygen production of prodigiosenes
Huguette Savoie1, Carlotta Figliola2, Estelle Marchal2
1Department of Chemistry, University of Hull, Cottingham Road, Hull, HU6 7RX, UK. r.w.boyle@hull.ac.uk.
Abstract:
The photo-induced cytotoxicity of prodigiosenes is reported. One prodigiosene represents a synthetic analogue of the natural product prodigiosin, and two are conjugated to molecules that target the estrogen receptor (ER). A comparison of incubation and irradiation frameworks for the three prodigiosenes is reported, with activity against ER- and ER+ lines explored. Furthermore, the ability of the three prodigiosenes to photosensitise the production of singlet oxygen is demonstrated, shedding mechanistic light onto possible photodynamic therapeutic effects of this class of tripyrroles.
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