Related Experiment Video
Updated: Feb 11, 2026
06:54
Dissection of Human Retina and RPE-Choroid for Proteomic Analysis
Published on: November 12, 2017
11.9K
Proteomics in Human Reproduction.
Mauro Bibancos De Rose1,2,3, Mariana Moraes Piccolomini4, Andrea Sammartino Soares Belo4
1Fertility Medical Group, Av. Brigadeiro Luiz Antonio, 4545, Sao Paulo - 04511-010, Brazil.
Protein and Peptide Letters
|April 14, 2018
Summary
Proteomics offers a promising non-invasive approach to improve infertility diagnosis and embryo selection in Assisted Reproduction Technologies (ART), potentially enhancing success rates and contributing to healthy births.
Area of Science:
- Reproductive Biology
- Biochemistry
- Medical Technology
Background:
- Assisted Reproduction Technologies (ART) have advanced significantly, but embryo implantation remains a challenge.
- Accurate infertility diagnosis and assessment of gamete/embryo viability are crucial for successful ART.
- Identifying embryos with the highest implantation potential is a key goal in ART.
Purpose of the Study:
- To review the role of proteomics in Assisted Reproduction Technologies (ART).
- To evaluate proteomics as a potential future tool for ART.
Main Methods:
- A literature review was conducted on proteomics and assisted reproduction.
- Focus on non-invasive approaches for diagnosis and assessment.
Main Results:
- Proteomic profiling and other omics technologies offer non-invasive methods to assess embryo development potential.
- These approaches enhance understanding of embryo physiology.
- Methods to predict developmental competence and viability can be developed.
Conclusions:
- Proteomics can identify oocytes and embryos with superior developmental potential.
- Proteomics may aid in diagnosing male and female infertility.
- Proteomics could become a valuable laboratory tool for achieving healthy births.
Related Concept Videos
01:27Reproductive Cloning
32.8K
Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
32.8K
01:33Proteomics
9.9K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
9.9K
02:38Asexual Reproduction
37.5K
Asexual reproduction allows plants to reproduce without growing flowers, attracting pollinators, or dispersing seeds. Offspring are genetically identical to the parent and produced without the fusion of male and female gametes.
37.5K
01:31Overview of the Reproductive System
5.7K
The reproductive system generates offspring, ensuring the survival of the species. In humans, the reproductive system is complex and involves a variety of organs and hormones that work together to ensure successful reproduction.
The gonads, or primary reproductive organs, produce gametes and sex hormones. In males, the testes produce spermatozoa and testosterone, which is responsible for developing secondary male sex characteristics, including a deeper voice, larger muscles, facial and body...
The gonads, or primary reproductive organs, produce gametes and sex hormones. In males, the testes produce spermatozoa and testosterone, which is responsible for developing secondary male sex characteristics, including a deeper voice, larger muscles, facial and body...
5.7K
01:20Disorders of the Male Reproductive System
5.1K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.1K
01:24Disorders of the Female Reproductive System
4.5K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
4.5K