Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethical Issues01:27

Ethical Issues

2.3K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
2.3K
The Thyroid Gland01:23

The Thyroid Gland

7.8K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.8K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

6.3K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.3K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

5.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.7K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.0K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.0K
Tonsillitis II: Management01:26

Tonsillitis II: Management

445
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
445

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of Differentiated Thyroid Cancer.

The New England journal of medicine·2026
Same author

Active Surveillance in Papillary Thyroid Cancer With Primary Tumors Greater Than 1.5 cm.

Head & neck·2026
Same author

Exposure to GLP-1RA and Risk of Structural Progression in Differentiated Thyroid Cancer.

The Journal of clinical endocrinology and metabolism·2026
Same author

Thyroid Lobectomy and Neck Dissection for N1b Papillary Thyroid Carcinoma.

JAMA otolaryngology-- head & neck surgery·2025
Same author

Effect of GLP-1 Receptor Agonists on Patients with Thyroid Carcinomas Undergoing Active Surveillance.

Journal of the Endocrine Society·2025
Same author

Clinical and genomic characterization of brain metastasis in thyroid cancer.

Journal of neuro-oncology·2025
Same journal

Overall Survival with [<sup>177</sup>Lu]Lu-PSMA-617 Versus [<sup>177</sup>Lu]Lu-PSMA I&T: A Propensity Score-Matched Real-World Analysis.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Toward a Biopsy-Free Diagnosis of Prostate Cancer: Potential of Combined <sup>18</sup>F-Flotufolastat PSMA PET and mpMRI.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

PSMA PET/CT-Targeted Biopsy in Men with Negative or Equivocal Multiparametric MRI and Exploratory Dynamic Total-Body PET: The FUPERMAN Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Erratum.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Live from 2026 SNMMI Annual Meeting in Los Angeles!

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

CAR T-Cell Therapy for Cancer: Updates and Challenges for Response Assessment.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

2.3K

Controversial Issues in Thyroid Cancer Management.

R Michael Tuttle1

  • 1Endocrinology Service, Memorial Sloan Kettering Cancer Center, New York, New York tuttlem@mskcc.org.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|April 15, 2018
PubMed
Summary
This summary is machine-generated.

Differentiated thyroid cancer management lacks high-quality trials, leading to controversy. This review examines thyroid lobectomy, preoperative imaging, and radioactive iodine use for personalized, risk-adapted patient care.

Keywords:
radioactive iodine therapythyroid cancerthyroid lobectomy

More Related Videos

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

1.0K
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.5K

Related Experiment Videos

Last Updated: Feb 11, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

2.3K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

1.0K
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.5K

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Nuclear Medicine

Background:

  • Limited prospective randomized clinical trials in differentiated thyroid cancer necessitate reliance on retrospective data.
  • Retrospective data are often incomplete, prone to selection bias, and yield conflicting evidence.
  • This leads to unresolved controversies in managing differentiated thyroid cancer.

Purpose of the Study:

  • To review and discuss controversies in three key areas of differentiated thyroid cancer management.
  • To provide insights for a risk-adapted, personalized approach to thyroid cancer treatment.
  • To aid clinicians and patients in balancing risks and benefits for optimized care.

Main Methods:

  • Review of existing literature on differentiated thyroid cancer management.
  • Focus on three controversial topics: thyroid lobectomy, preoperative neck imaging, and radioactive iodine use.
  • Analysis of evidence to support risk-adapted and personalized treatment strategies.

Main Results:

  • Thyroid lobectomy as initial therapy presents options and considerations.
  • Preoperative neck imaging's role in optimizing surgical completeness is examined.
  • Selective use of radioactive iodine for remnant ablation, adjuvant therapy, or persistent/recurrent disease is discussed.

Conclusions:

  • Differentiated thyroid cancer management is evolving towards personalized, risk-adapted strategies.
  • Balancing treatment risks and benefits with patient values is crucial.
  • Optimized management requires collaboration between clinicians and patients, considering local expertise.