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Liver Doppler Findings in Pediatric Patients After Total Pancreatectomy and Islet Autotransplantation

Tara L Holm1, Michael A Murati1, Eric Hoggard1

  • 1Department of Radiology, University of Minnesota, Minneapolis, Minnesota, USA.

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
|April 16, 2018
PubMed

Insights

This study establishes normal Doppler velocities for pediatric patients undergoing total pancreatectomy and islet autotransplantation (TPIAT). Portal vein thrombosis is rare, and a broad range of vascular velocities are considered normal post-TPIAT.

Area of Science:

  • Pediatric Surgery
  • Vascular Imaging
  • Transplantation Medicine

Background:

  • Total pancreatectomy and islet autotransplantation (TPIAT) is a complex procedure in pediatric patients.
  • Assessing liver vascular health post-TPIAT is crucial for patient outcomes.
  • Establishing normal vascular flow parameters is essential for accurate interpretation of imaging studies.

Purpose of the Study:

  • To determine normal Doppler velocity values in the hepatic artery and portal veins of pediatric patients following TPIAT.
  • To provide reference ranges for hepatic artery resistive index in this population.
  • To evaluate the incidence of hepatic vascular complications after TPIAT.

Main Methods:

  • Retrospective review of liver Doppler studies in pediatric patients who underwent TPIAT.
  • Analysis of Doppler velocities in the hepatic artery and portal vein.
  • Calculation of hepatic artery resistive index.

Main Results:

  • Sixty-five pediatric patients were included in the study.
  • No cases of portal vein thrombosis or other hepatic vascular complications were observed.
  • Mean hepatic artery peak systolic velocity was 157.6 cm/s (±60.9 cm/s), mean resistive index was 0.57 (±0.09), and mean portal vein velocity was 31.9 cm/s (±12.9 cm/s).

Conclusions:

  • Portal vein thrombosis is infrequent in pediatric patients post-TPIAT.
  • A wide spectrum of hepatic artery and portal vein velocities can be considered normal in children immediately after TPIAT, in the absence of vascular complications.
Abstract

Keywords:
DopplerDoppler (abdominal)islet autotransplantationislet cellpancreatectomypancreatitispediatrics

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