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Updated: Feb 11, 2026
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
Randomized controlled clinical study assessing two membranes for guided bone regeneration of peri-implant bone
Tobias Basler1, Nadja Naenni1, David Schneider1
1Clinic of Fixed and Removable Prosthodontics and Dental Material Science, University of Zurich, Zurich, Switzerland.
Objectives:
To assess two- and three-dimensional changes of the peri-implant tissues as well as clinical, biological, and radiological outcomes of implants having been treated with resorbable or nonresorbable membranes at 3 years.
Materials And Methods:
Twenty-three patients were re-examined after having received a single-tooth implant in the esthetic zone in conjunction with guided bone regeneration (GBR) using either a resorbable (RES) or a titanium-reinforced nonresorbable membrane (N-RES) and demineralized bovine bone mineral. Volumetric and linear as well as clinical and radiographic measurements were performed at crown insertion (baseline), at 1 year (FU-1) and 3 years (FU-3). Statistics were performed by means of parametric and nonparametric tests.
Results:
Minor, but ongoing buccal volume loss was observed in both groups during the 3-year follow-up. A slightly higher volume loss was observed in group RES (-0.22 mm) compared to N-RES (-0.14 mm) at 1 year (FU-1), but aligned at 3 years (FU-3) RES (-0.30 mm) N-RES (-0.32 mm). All changes over time were statistically significantly different within (p < .05), but not between the groups (p > .05). Stable median interproximal bone levels after 3 years (FU-3); 0.26 mm (0.04; 0.36) (RES) and 0.14 mm (0.08; 0.20) (N-RES) and healthy tissues (BOP, PD) were obtained with both membranes.
Conclusions:
Both treatment modalities resulted in minor, but ongoing contour changes of the peri-implant tissues. Stable interproximal bone levels and healthy tissues can be obtained with membranes up to 3 years.
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