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Acute pancreatitis in children.
Urszula Grzybowska-Chlebowczyk1, Martyna Jasielska2, Anna Flak-Wancerz2
1Department of Paediatrics, School of Medicine, Medical University of Silesia, Katowice, Poland.
Przeglad Gastroenterologiczny
|April 17, 2018
Summary
Idiopathic acute pancreatitis is most common in children, highlighting the need for further research into genetic causes, especially in younger patients. This study analyzed 51 children over ten years.
Area of Science:
- Pediatric Gastroenterology
- Pancreatology
- Medical Genetics
Background:
- Acute pancreatitis is increasingly diagnosed in children.
- Understanding its incidence and causes in pediatric populations is crucial.
Purpose of the Study:
- To conduct a retrospective analysis of acute pancreatitis in children.
- To determine the incidence, aetiology, and clinical course of the disease.
Main Methods:
- Retrospective analysis of medical records from January 2004 to December 2013.
- Inclusion of patients hospitalized in the Gastroenterology Unit of the Paediatrics Department.
- Diagnosis based on INSPIRE criteria and modified Atlanta classification.
Main Results:
- 76 cases of acute pancreatitis in 51 children (average age 12.07 years).
- Idiopathic aetiology was most common (43.1%), followed by biliary causes (29.4%).
- Genetic causes identified in 15.7% of patients, including PRSS1, SPINK1, and CFTR mutations.
Conclusions:
- Idiopathic acute pancreatitis is the most frequent diagnosis in pediatric patients.
- Further investigation into genetic factors is warranted, particularly for younger children.
- Continued research is essential to uncover underlying causes of pediatric acute pancreatitis.
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