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Surgical Treatment of Annuloaortic Ectasia - Replace or Repair?
Andrea De Martino1, Federico Del Re1, Stefania Blasi1
1Section of Cardiac Surgery, Cardiac Thoracic and Vascular Department, University Hospital, Pisa, Italy.
Insights
The David I procedure offers safe and reproducible aortic valve repair for annuloaortic ectasia, showing excellent long-term results. The modified Bentall procedure had more complications, but longer follow-up is needed for a definitive comparison.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Surgery
Background:
- Annuloaortic ectasia necessitates surgical intervention, with modified Bentall and David I valve-sparing procedures being common options.
- This study compares the long-term outcomes of these two surgical techniques in patients with annuloaortic ectasia.
Purpose of the Study:
- To compare the long-term results of modified Bentall versus David I valve-sparing procedures for annuloaortic ectasia.
- To evaluate the safety, efficacy, and complication rates of each surgical approach.
Main Methods:
- A retrospective analysis of 181 patients with annuloaortic ectasia who underwent either modified Bentall (n=102) or David I (n=79) procedures between 1994 and 2015.
- Patient groups were compared based on demographics, preoperative health status, and surgical outcomes including mortality, thromboembolism, hemorrhage, endocarditis, survival, and reoperation rates.
Main Results:
- Early mortality was low and similar between groups (3% modified Bentall vs. 2.5% David I).
- Modified Bentall was associated with higher rates of thromboembolism and hemorrhage; David I had higher endocarditis rates.
- Actuarial survival at 10-15 years favored David I (84% vs. 70%), with excellent freedom from reoperation for both (97% modified Bentall, 84% David I). No moderate/severe aortic regurgitation was noted.
Conclusions:
- Both modified Bentall and David I procedures demonstrate excellent early and late outcomes for annuloaortic ectasia.
- The David I procedure is favored due to its safety, reproducibility, and stable aortic valve repair, despite a higher incidence of endocarditis.
- While the modified Bentall procedure carries risks of thromboembolic and hemorrhagic complications, the shorter follow-up for David I limits direct long-term comparison.
Background:
Patients with annuloaortic ectasia may be surgically treated with modified Bentall or David I valve-sparing procedures. Here, we compared the long-term results of these procedures.
Methods:
A total of 181 patients with annuloaortic ectasia underwent modified Bentall (102 patients, Group 1) or David I (79 patients, Group 2) procedures from 1994 to 2015. Mean age was 62 ± 11 years in Group 1 and 64 ± 16 years in Group 2. Group 1 patients were in poorer health, with a lower ejection fraction and higher functional class.
Results:
Early mortality was 3% in Group 1 and 2.5% in Group 2. Patients undergoing a modified Bentall procedure had a higher incidence of thromboembolism and hemorrhage, whereas those undergoing a David I procedure had a higher incidence of endocarditis. Actuarial survival was 70 ± 6% at 15 years in Group 1 and 84 ± 7% at 10 years in Group 2. Actuarial freedom from reoperation was 97 ± 2% at 15 years in Group 1 and 84 ± 7% at 10 years in Group 2. In Group 2, freedom from procedure-related reoperations was 98 ± 2% at 10 years. At last follow-up, no cases of moderate or severe aortic regurgitation were observed.
Conclusions:
The modified Bentall and David I procedures showed excellent early and late results. The modified Bentall procedure with a mechanical conduit was associated with thromboembolic and hemorrhagic complications, whereas the David I procedure was associated with unexplained occurrences of endocarditis. Thus, the David I procedure appears to be safe, reproducible, and capable of achieving stable aortic valve repair and is therefore our currently preferred solution for patients with annuloaortic ectasia. However, the much shorter follow-up for David I patients limits the strength of our comparison between the two techniques.
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