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Updated: Feb 11, 2026

Processing of Bulk Nanocrystalline Metals at the US Army Research Laboratory
Published on: March 7, 2018
Effect of Nanocrystalline Particles of Chitin on Blood Components in Humans and Experimental Animals
N N Drozd1, M A Torlopov2, E V Udoratina2
1Hematology Research Center, Ministry of Health of the Russian Federation, Moscow, Russia. nndrozd@mail.ru.
Abstract:
Nanocrystalline particles of chitin in the form of hydrosol in a concentration of 0.63 mg/ml have no effect on aggregation of human platelets and clotting time of platelet-poor plasma in coagulation tests. ADP-induced aggregation of human platelets was inhibited by these nanoparticles in concentrations of 0.63 and 1.00 mg/ml in comparison with the control. Intravenous administration of nanoparticles in a dose of 1 mg/kg to guinea pigs produced no anticoagulant effect. The nanocrystalline particles of chitin can be of interest as potential drug delivery systems.
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