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Does Hyperglycemia Affect Risk of Peripherally Inserted Central Catheter-Related Upper Extremity Venous Thrombosis?
James D Wilson1, José H Guardiola, Brady Simonak
1Christus Health/Texas A&M College of Medicine-Spohn Hospital Program/Family Medicine, Corpus Christi, Texas (Dr Wilson); Texas A&M University-Corpus Christi, Corpus Christi, Texas (Dr Guardiola); Fossil Creek Family Medicine Center, Fort Worth, Texas (Dr Simonak); Fossil Creek Family Medicine Center, Fort Worth, Texas (Dr Wenhold); and Christus Spohn Hospital, Beeville, Texas (Dr Wenhold). James D. Wilson, MD, FAAFP, is a faculty physician at the Christus Health/Texas A&M College of Medicine-Spohn Hospital Program/Family Medicine. He is also a medical officer in the US Army Reserve. José H. Guardiola, PhD, is an associate professor of mathematics and statistics at Texas A&M University. Brady Simonak, DO, is a family medicine physician at Fossil Creek Family Medicine Center. John Wenhold, DO, is a family physician at Christus Spohn Beeville.
Abstract:
It is not clear whether blood glucose (BG) affects the risk of peripherally inserted central catheter (PICC)-related upper extremity venous thrombosis (PRUEVT). A case-control study was conducted comparing patients with PRUEVT versus patients with PICCs who did not develop PRUEVT. BG on admission was significantly higher among cases with PRUEVT than controls. No significant differences were found between the groups in hemoglobin A1c or BG on the third day of hospitalization. PRUEVT cases were more likely to be diabetic, but this did not reach statistical significance. The time that a PICC was in place before PRUEVT was diagnosed was longer for diabetic patients, but the authors believe this result must be viewed with caution.
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