Sample preparation in foodomic analyses

Area of Science:

• Foodomics
• Analytical Chemistry
• Biotechnology

Background:

• Representative sampling and adequate sample preparation are crucial for accurate foodomics analyses.
• Improper techniques can introduce significant bias, which cannot be corrected later in the analytical process.
• Historically neglected, these pre-analytical steps are now gaining critical attention in foodomics research.

Purpose of the Study:

• To review the progress in sampling and sample preparation techniques within the field of foodomics.
• To highlight advancements in instrumentation and methodologies for foodomics.
• To emphasize the importance of these foundational steps for reliable omics data.

Main Methods:

• Review of current literature and technological advancements in foodomics sampling and sample preparation.
• Discussion of sophisticated instrumentation for high-performance and high-throughput analyses.
• Exploration of miniaturization and laboratory robotics applications in omics.

Main Results:

• Significant progress has been made in developing advanced sampling and sample preparation methods for foodomics.
• Sophisticated instruments, miniaturization, and laboratory robotics are increasingly employed to enhance efficiency and accuracy.
• These advancements support high-performance and high-throughput analyses in metabolomics, proteomics, peptidomics, and genomics.

Conclusions:

• Improvements in sampling and sample preparation are vital for the success of foodomics studies.
• Technological innovations are enhancing the reliability and throughput of pre-analytical steps.
• Adoption of advanced techniques ensures the integrity of data interpretation in various foodomics disciplines.