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Updated: Feb 11, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Office-based endoscopic botulinum toxin injection in laryngeal movement disorders
A Kaderbay1, C A Righini2, P F Castellanos3
1Clinique universitaire d'ORL, CHU Grenoble Alpes, BP 217, 38043 Grenoble cedex 09, France; Université Grenoble Alpes, CS 40700, 38058 Grenoble cedex 9, France.
Introduction:
Botulinum toxin injection is widely used for the treatment of laryngeal movement disorders. Electromyography-guided percutaneous injection is the technique most commonly used to perform intralaryngeal botulinum toxin injection.
Objective:
We describe an endoscopic approach for intralaryngeal botulinum toxin injection under local anaesthesia without using electromyography.
Technique:
A flexible video-endoscope with an operating channel is used. After local anaesthesia of the larynx by instillation of lidocaine, a flexible needle is inserted into the operating channel in order to inject the desired dose of botulinum toxin into the vocal and/or vestibular folds.
Conclusion:
Endoscopic botulinum toxin injection under local anaesthesia is a reliable technique for the treatment of laryngeal movement disorders. It can be performed by any laryngologist without the need for electromyography. It is easy to perform for the operator and comfortable for the patient.
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