Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Resonance02:52

Resonance

66.0K
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds.
66.0K
Series Resonance01:17

Series Resonance

877
The RLC circuit impedance is defined as the ratio of the supply voltage to the circuit current. Resonance in such a circuit occurs when the imaginary part of this impedance equals zero. This specific condition means that the inductive reactance is exactly equal to the capacitive reactance. The frequency at which this happens is known as the resonant frequency. Mathematically, the resonant frequency is inversely proportional to the square root of the product of the inductance (L) and capacitance...
877
Parallel Resonance01:23

Parallel Resonance

601
The parallel RLC circuit is an arrangement where the resistor (R), inductor (L), and capacitor (C) are all connected to the same nodes and, as a result, share the same voltage across them. The parallel RLC circuit is analyzed in terms of admittance (Y), which reflects the ease with which current can flow. The admittance is given by:
601
Sound Waves: Resonance01:14

Sound Waves: Resonance

3.5K
Resonance is produced depending on the boundary conditions imposed on a wave. Resonance can be produced in a string under tension with symmetrical boundary conditions (i.e., has a node at each end). A node is defined as a fixed point where the string does not move. The symmetrical boundary conditions result in some frequencies resonating and producing standing waves, while other frequencies interfere destructively. Sound waves can resonate in a hollow tube, and the frequencies of the sound...
3.5K
Resonance and Hybrid Structures02:16

Resonance and Hybrid Structures

27.1K
According to the theory of resonance, if two or more Lewis structures with the same arrangement of atoms can be written for a molecule, ion, or radical, the actual distribution of electrons is an average of that shown by the various Lewis structures.
Resonance Structures and Resonance Hybrids
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N–O and N=O bonds.
27.1K
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

9.8K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
9.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PyEvoMotion: a Python tool for population-based time-course analysis of genome evolution.

Bioinformatics (Oxford, England)·2026
Same author

CRISPR-Cas9 trans-cleavage is hindered by a flanked R-loop, an elongated spacer, and an inactive HNH domain.

Nature communications·2026
Same author

Detection of tomato brown rugose fruit virus through CRISPR-Cas12a and CRISPR-Cas9 systems.

Scientific reports·2025
Same author

Arabidopsis thaliana iron superoxide dismutase FeSOD1 protects ARGONAUTE 1 in a copper-dependent manner.

Journal of experimental botany·2025
Same author

Digitizing the Blue Light-Activated T7 RNA Polymerase System with a <i>tet</i>-Controlled Riboregulator.

ACS synthetic biology·2025
Same author

Virus Detection by CRISPR-Cas9-Mediated Strand Displacement in a Lateral Flow Assay.

ACS applied bio materials·2025

Related Experiment Video

Updated: Feb 11, 2026

Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions
09:36

Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions

Published on: August 26, 2021

4.5K

Suprathreshold Stochastic Resonance behind Cancer.

Guillermo Rodrigo1, Nigel G Stocks2

  • 1Institute for Integrative Systems Biology, Consejo Superior de Investigaciones Científicas (CSIC), University of Valencia, Paterna 46980, Spain.

Trends in Biochemical Sciences
|April 19, 2018
PubMed
Summary

Gene expression noise, or stochasticity, is crucial for cancer cells to develop resistance to therapies. This cellular defense mechanism is driven by the collective behavior of cell populations, not individual cells.

More Related Videos

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
06:22

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro

Published on: August 28, 2019

5.6K
Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model
06:24

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Published on: April 18, 2015

15.7K

Related Experiment Videos

Last Updated: Feb 11, 2026

Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions
09:36

Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions

Published on: August 26, 2021

4.5K
Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
06:22

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro

Published on: August 28, 2019

5.6K
Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model
06:24

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Published on: April 18, 2015

15.7K

Area of Science:

  • Molecular Biology
  • Cancer Research
  • Systems Biology

Background:

  • Gene expression exhibits inherent stochasticity (noise), which can be functionally significant.
  • Cancer cells leverage this noise to enhance population heterogeneity, aiding survival against treatments.

Purpose of the Study:

  • To investigate the role of noise in gene expression within cancer cell populations.
  • To elucidate the mechanisms by which cellular noise contributes to therapeutic resistance.

Main Methods:

  • Analysis of stochastic resonance phenomena in biological systems.
  • Modeling of collective cell behavior and its impact on population heterogeneity.

Main Results:

  • Stochastic resonance, driven by collective cellular activity, underlies the functional role of gene expression noise.
  • Cancer cell populations utilize this collective stochasticity to evade therapies.

Conclusions:

  • The functional role of gene expression noise in cancer is mediated by collective cell behavior.
  • Understanding collective stochastic resonance is key to developing novel cancer therapies.