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Updated: Feb 11, 2026

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Devil is in the detail.

John Roshan Jacob1, Amal Paul1, Anoop George Alex1

  • 1Department of cardiac electrophysiology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

BMJ Case Reports
|April 19, 2018
PubMed
Summary
This summary is machine-generated.

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A young girl

Area of Science:

  • Cardiology
  • Genetics

Background:

  • A 15-year-old girl experienced recurrent dizziness and syncope for 3 years.
  • Initial evaluations for cardiac and neurological causes were normal, leading to a suspected diagnosis of psychogenic syncope.

Observation:

  • Episodes were triggered by emotional/physical stress and relieved by rest.
  • Family history revealed unexplained deaths in siblings, potentially sudden cardiac deaths.

Findings:

  • Treadmill testing identified exercise-induced polymorphic ventricular tachycardia.
  • Diagnosis confirmed as catecholaminergic polymorphic ventricular tachycardia.

Implications:

  • Highlights the importance of thorough family history in diagnosing inherited cardiac conditions.
Keywords:
arrhythmiascongenital disordersgenetic screening / counsellingpacing and electrophysiology

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  • Beta-blocker therapy proved effective, suggesting a viable treatment strategy for this condition.