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Updated: Feb 11, 2026

Quantification of Lipid Abundance and Evaluation of Lipid Distribution in Caenorhabditis elegans by Nile Red and Oil Red O Staining
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Red Cell Distribution Width (RDW): Normative Data in Indian Neonates.

Saumil A Desai1, Snehal L Martin2, Ruchi N Nanavati1

  • 1Department of Neonatology, KEM Hospital.

Journal of Pediatric Hematology/Oncology
|April 19, 2018
PubMed
Summary
This summary is machine-generated.

Red cell distribution width (RDW) is higher in Indian preterm neonates, especially those with fetal growth restriction (FGR). These RDW values exceed those found in Western neonates, suggesting FGR impacts RDW in this population.

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Area of Science:

  • Neonatal Medicine
  • Hematology
  • Pediatric Growth Studies

Background:

  • Red cell distribution width (RDW) is a measure of red blood cell size variation.
  • Prematurity and fetal growth restriction (FGR) are known to affect RDW.
  • Establishing population-specific normal ranges is crucial for accurate diagnosis.

Purpose of the Study:

  • To determine normal Red cell distribution width (RDW) values in Indian neonates.
  • To investigate the influence of prematurity and fetal growth restriction (FGR) on RDW in this population.
  • To compare RDW values in Indian neonates with FGR to existing Western data.

Main Methods:

  • Prospective observational study design.
  • Inclusion of 964 Indian neonates with significant FGR.
  • Analysis of Red cell distribution width (RDW) values based on gestational age and FGR status.

Main Results:

  • Mean RDW values were significantly higher in preterm neonates compared to term neonates (P<0.0004).
  • RDW values in Indian neonates with FGR were significantly higher than their Western counterparts (P<0.0001).
  • Mean RDW values across different gestational ages in Indian neonates exceeded those reported in other studies.

Conclusions:

  • Indian neonates, particularly those with FGR, exhibit higher RDW values than previously reported.
  • The findings suggest that FGR is a significant contributing factor to elevated RDW in Indian neonates.
  • Further research is warranted to understand the specific mechanisms and clinical implications of these findings.