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Updated: Feb 11, 2026

Computer-Generated Animal Model Stimuli
Published on: July 29, 2007
Utilizing Animal Models of Infantile Spasms
1Department of Neuroscience, Tufts University School of Medicine, Boston, MA.
Abstract:
Infantile spasms are a devastating epileptic encephalopathy characterized by early life spasms and later seizures. Clinical outcomes of infantile spasms are poor and therapeutic options are limited with significant adverse effects. Therefore, new strategies to treat infantile spasms are of the utmost importance. Animals models of infantile spasms are a critical component of developing new therapies. Here, we review current chronic animal models of infantile spasms and consider future advances that may help improve patient care, as well as our scientific understanding of this debilitating disease.
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