Left Circumflex Artery Rupture with Left Atrial Tamponade and Functional Mitral Stenosis
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Updated: Feb 11, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
Weiting Huang1, Khaled Mohamed Emadeldin Moheb Hammad2, Victor Tar Toong Chao1
1National Heart Centre Singapore, Singapore.
Insights
Percutaneous transluminal coronary interventions can lead to rare but serious complications. This case highlights how left circumflex artery perforation can cause left atrial and coronary sinus compression, resulting in functional mitral stenosis.
Area of Science:
- Interventional Cardiology
- Cardiac Anatomy
- Vascular Complications
Background:
- Percutaneous transluminal devices allow treatment of complex coronary anatomy.
- Complications like dissection, perforation, and acute coronary syndrome occur, with mortality up to 4.2%.
Observation:
- Left circumflex artery perforation is of particular concern due to its anatomical location.
- Fluid accumulation in the oblique sinus can compress the left atrium and coronary sinus.
Findings:
- A case of left circumflex artery perforation is presented.
- This perforation led to significant compression of the coronary sinus and left atrium.
Implications:
- The compression resulted in functional mitral stenosis.
- Understanding these rare complications is crucial for managing complex percutaneous interventions.
Abstract:
The growth in percutaneous transluminal devices has enabled operators to tackle more complex, native, and post-bypass surgery anatomy. However, complications such as coronary artery dissection, coronary perforation, retrograde aortic dissection, arrhythmias, and acute coronary syndrome still occur with resulting mortality rates of up to 4.2% in complex interventions. Perforation of the circumflex artery is of particular interest in view of its position and relation to the surrounding cardiac structures. This is a site of potential fluid collection, and as the left atrium is fixed to the parietal pericardium at the entry of the pulmonary veins, fluid in the oblique sinus can accumulate enough pressure to compress the left atrium and the coronary sinus. We present a case of left circumflex artery perforation which demonstrates the physiologic complications of coronary sinus and left atrial compression and the resultant functional mitral stenosis.
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