Related Experiment Video
Updated: Feb 11, 2026

Efficient Differentiation of Human Pluripotent Stem Cells into Liver Cells
Published on: June 11, 2019
Current Perspectives Regarding Stem Cell-Based Therapy for Liver Cirrhosis
Kyeong-Ah Kwak1, Hyun-Jae Cho2, Jin-Young Yang3
1Department of Oral Anatomy, School of Dentistry, Seoul National University and Dental Research Institute, Seoul, Republic of Korea.
Abstract:
Liver cirrhosis is a major cause of mortality and a common end of various progressive liver diseases. Since the effective treatment is currently limited to liver transplantation, stem cell-based therapy as an alternative has attracted interest due to promising results from preclinical and clinical studies. However, there is still much to be understood regarding the precise mechanisms of action. A number of stem cells from different origins have been employed for hepatic regeneration with different degrees of success. The present review presents a synopsis of stem cell research for the treatment of patients with liver cirrhosis according to the stem cell type. Clinical trials to date are summarized briefly. Finally, issues to be resolved and future perspectives are discussed with regard to clinical applications.
Related Concept Videos
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Adult Stem Cells
Psychodynamic Perspectives on Personality
Psychodynamic theorists argue that unconscious...
Embryonic Stem Cells
Induced Pluripotent Stem Cells
Social Cognitive Perspective on Personality

