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Updated: Feb 11, 2026

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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published on: September 21, 2017
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Four-Strand Versus 2-Strand Suture-Button Constructs in First Carpometacarpal Arthroplasty: A Biomechanical Study.
Beatrice L Grasu1, Andrew J Trontis1, Brent G Parks1
1The Curtis National Hand Center, Baltimore, MD, USA.
Summary
Both 4-strand and 2-strand suture-button constructs offer similar stability for first carpometacarpal (CMC) joint surgery. The 2-strand method
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Hand Surgery
Background:
- First carpometacarpal (CMC) arthritis treatment often involves trapeziectomy.
- Suture-button fixation is an alternative to other fixation methods like Kirschner wires.
- A 2-strand construct uses a smaller tunnel than a 4-strand construct, potentially reducing fracture risk.
Purpose of the Study:
- To compare the biomechanical stability and failure modes of 4-strand versus 2-strand suture-button constructs.
- To evaluate these constructs in a biomechanical model simulating first CMC joint arthroplasty.
Main Methods:
- Ten matched pairs of cadaveric hands were used.
- Hands were randomized to receive either a 4-strand or 2-strand suture-button device after trapeziectomy.
- Constructs underwent 1000 cycles of loading, followed by load-to-failure testing.
Main Results:
- No significant differences in joint height or load to failure were observed between the 4-strand and 2-strand groups.
- Failure mechanisms varied, with 4-strand constructs failing through the first ray and 2-strand constructs experiencing suture failure.
- Pinch pressure showed no significant difference between the groups.
Conclusions:
- Both 4-strand and 2-strand suture-button constructs demonstrate comparable biomechanical stability for first CMC arthroplasty.
- The 2-strand construct, utilizing a smaller tunnel, may offer an advantage due to potentially lower risk of metacarpal fracture.
Keywords:
CMC arthroplastyfirst metacarpal subsidenceload to failure of constructssuture-button constructthumb pinch strengthMore Related Videos
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