Keratoprosthesis: Current global scenario and a broad Indian perspective

Area of Science:

• Ophthalmology
• Corneal Surgery
• Prosthetic Devices

Background:

• Keratoprosthesis (Kpro) is a critical intervention for bilateral end-stage corneal blindness.
• Common Kpro types include Boston Type 1 and 2, modified osteo-odonto Kpro, and osteo-Kpro.
• Recent years show a global increase in Kpro procedures, including in India.

Purpose of the Study:

• To compile and review current worldwide data on frequently performed Kpro types.
• To compare Kpro indications and outcomes globally with those in the Indian context.
• To address the growing need for ophthalmologist awareness regarding Kpro indications and management.

Main Methods:

• Systematic review of large, single-center studies on Boston Type 1 and 2, modified osteo-odonto Kpro, and osteo-Kpro.
• Analysis of indications, surgical techniques, and patient outcomes.
• Comparative analysis of global Kpro data versus the Indian scenario.

Main Results:

• Indications for Kpro have broadened significantly over time.
• Complications associated with Kpro have decreased due to design and post-operative care improvements.
• A notable surge in Kpro procedures has been observed globally and within India over the past decade.

Conclusions:

• Kpro procedures demand specialized infrastructure and long-term patient commitment.
• Enhanced awareness among Indian ophthalmologists about Kpro indications and management is crucial for appropriate patient referral and care.
• Corneal specialists require deeper understanding of Kpro nuances for optimal patient and device selection.