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Nitrous oxide and day-case laparoscopy: effects on nausea, vomiting and return to normal activity
1Department of Anaesthetics, St Thomas' Hospital, London.
British Journal of Anaesthesia
|April 1, 1988
Summary
Nitrous oxide can be omitted during laparoscopic surgery anesthesia without impacting postoperative nausea, vomiting, or recovery time. This finding supports avoiding nitrous oxide in day-case laparoscopy.
Area of Science:
- Anesthesiology
- Surgical Patient Care
Background:
- Day-case laparoscopy is a common surgical procedure.
- Anesthetic techniques aim to minimize postoperative morbidity and facilitate rapid recovery.
Purpose of the Study:
- To evaluate the impact of omitting nitrous oxide on postoperative outcomes in patients undergoing day-case laparoscopy.
- To assess nausea, vomiting, and return to normal activity after anesthesia with or without nitrous oxide.
Main Methods:
- Randomized controlled trial comparing nitrous oxide-oxygen with oxygen-enflurane anesthesia.
- Assessment of postoperative nausea, vomiting, analgesic/anti-emetic requirements, and time to resume normal activity over 48 hours.
Main Results:
- Propofol supplementation was needed more often without nitrous oxide (P<0.05).
- No significant difference in vomiting incidence before discharge.
- Similar incidence and severity of nausea, analgesic/anti-emetic needs, and time to resume normal activity between groups.
Conclusions:
- Nitrous oxide can be omitted in day-case laparoscopy without adversely affecting postoperative morbidity.
- Avoiding nitrous oxide does not prolong recovery time or impact return to normal activity.