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Related Concept Videos

Genomics02:02

Genomics

36.0K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Reproductive Cloning01:27

Reproductive Cloning

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Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
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Proteomics01:33

Proteomics

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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.2K
Cloning of Dolly the Sheep01:08

Cloning of Dolly the Sheep

3.4K
The first successfully cloned mammal was Dolly, a sheep, born on 5th July 1996 at Roslin Institute, Scotland. The cloned sheep was named after the American singer Dolly Parton. Dolly lived for seven years and died of respiratory complications, which is speculated to be due to the actual age of her DNA. Because the DNA in cloned cells belongs to an older individual,  the cloned individual’s life expectancy may be affected. Indeed, analysis of Dolly’s DNA revealed shorter...
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Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...

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Reusable Single Cell for Iterative Epigenomic Analyses
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Reproductomics: Exploring the Applications and Advancements of Computational Tools.

P Sengupta1, S Dutta, F Liew

  • 1Department of Biomedical Sciences, College of Medicine, Gulf Medical University, Ajman, UAE; Department of Life Science and Bioinformatics, Assam University, Silchar, India. shubhadeep1@gmail.com.

Physiological Research
|November 12, 2024
PubMed
Summary

Reproductomics integrates omics data to understand reproductive health. This field uses computational tools to analyze genetic and environmental factors, aiming to improve fertility treatments and outcomes.

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Area of Science:

  • Reproductive biology and bioinformatics.

Background:

  • Advancements in omics technologies have improved understanding of molecular mechanisms.
  • Reproductive disease data analysis is complex due to hormonal regulation, genetics, and environmental factors.

Purpose of the Study:

  • To explore reproductomics applications in understanding infertility.
  • To identify biomarkers for diagnosis and treatment.
  • To enhance assisted reproductive technologies (ARTs).

Main Methods:

  • Reproductomics utilizes computational tools to analyze reproductive data.
  • Includes machine learning for fertility prediction, gene editing, and single-cell sequencing.

Main Results:

  • Reproductomics offers insights into molecular mechanisms of reproductive processes.
  • Potential for improved diagnosis, treatment, and ARTs.

Conclusions:

  • Reproductomics holds significant potential for advancing reproductive health.
  • Addresses challenges, limitations, and ethical considerations of new technologies.