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Implementing Pharmacogenomic Clinical Decision Support into German Hospitals
Marc Hinderer1, Melanie Boerries2, Martin Boeker2
1Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.
Studies in Health Technology and Informatics
|April 22, 2018
Summary
Implementing pharmacogenomic Clinical Decision Support Systems (CDSS) in German hospitals faces legal uncertainty, data issues, and physician knowledge gaps. Structured pharmacogenomic reports may offer a feasible solution.
Area of Science:
- Medical Informatics
- Genetics
- Clinical Pharmacology
Background:
- Pharmacogenomic Clinical Decision Support Systems (CDSS) are key for integrating pharmacogenomic testing into routine clinical practice.
- Successful implementation requires addressing specific challenges within the German healthcare system.
Purpose of the Study:
- To identify and discuss critical factors for implementing pharmacogenomic CDSS in German hospitals.
- To analyze barriers and potential solutions for widespread adoption.
Main Methods:
- Analysis of two pertinent studies.
- Interviews with data privacy officers from three German university hospitals.
- Examination of relevant legal regulations and literature.
Main Results:
- Identified three primary barriers: legal uncertainty, lack of machine-readable data, and a knowledge gap in genetics and pharmacogenomics among physicians.
- Legal and data challenges pose significant hurdles to seamless integration.
Conclusions:
- Passive clinical decision support (CDS) using structured pharmacogenomic reports for somatic mutations presents a potentially feasible CDS feature for clinicians.
- This approach may mitigate some implementation barriers in German hospitals.
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