LSG vs MGB-OAGB-3 Year Follow-up Data: a Randomised Control Trial

Area of Science:

• Bariatric surgery outcomes
• Metabolic and bariatric surgery comparison
• Surgical treatment for obesity and comorbidities

Background:

• Obesity is a global health crisis requiring effective long-term management strategies.
• Bariatric surgical procedures like laparoscopic sleeve gastrectomy (LSG) and one anastomosis gastric bypass (MGB-OAGB) are established treatments.
• Comparative data on the long-term efficacy and safety of these procedures are crucial for clinical decision-making.

Purpose of the Study:

• To compare the 3-year follow-up outcomes of MGB-OAGB and LSG.
• To evaluate differences in weight loss, complication rates, comorbidity resolution, and quality of life.
• To provide evidence for the comparative effectiveness of these two bariatric procedures.

Main Methods:

• A prospective randomized controlled trial was conducted between 2012 and 2015.
• 100 patients underwent LSG and 101 patients underwent MGB-OAGB.
• Outcomes including percentage of excess weight loss (%EWL), complication rates, comorbidity resolution (diabetes, hypertension), and quality of life (BAROS score) were assessed at 3-year follow-up.

Main Results:

• At 3 years, average %EWL was 61.15% for LSG and 66.48% for MGB-OAGB (statistically insignificant difference).
• Diabetes remission rates were 81.82% for LSG and 89.13% for MGB-OAGB; hypertension remission rates were 72.22% for LSG and 74% for MGB-OAGB.
• MGB-OAGB patients reported a better quality of life, indicated by higher BAROS scores (6.96 vs 6.03 with comorbidities; 4.34 vs 3.86 without comorbidities).

Conclusions:

• No significant differences were observed between LSG and MGB-OAGB in %EWL and hypertension remission at 36 months.
• MGB-OAGB demonstrated higher, though statistically insignificant, type 2 diabetes mellitus remission rates compared to LSG.
• MGB-OAGB patients, particularly those with comorbidities, experienced a better quality of life post-surgery compared to LSG patients.