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Updated: Feb 11, 2026

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
07:27

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

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[Fungal keratitis: A 5-year monocentric retrospective study on Reunion Island]

G Hoarau1, M Albrieux2, T Martin-Phipps2

  • 1Service de bactériologie-virologie-parasitologie, CHU de La Réunion, BP 350, 97448 Saint-Pierre, Réunion.

Journal Francais D'Ophtalmologie
|April 24, 2018
PubMed
Abstract

Insights

Fungal keratitis, a severe eye infection, is predominantly caused by Fusarium species in Réunion Island. Prompt diagnosis and antifungal susceptibility testing are crucial for effective treatment, especially with Fusarium solani.

Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Background:

  • Fungal keratitis is a rare but sight-threatening eye infection.
  • Its epidemiology in tropical regions like Réunion Island requires detailed characterization.

Purpose of the Study:

  • To describe the epidemiology of fungal keratitis in Réunion Island.
  • To identify causative fungal species and their antifungal susceptibility.

Main Methods:

  • Retrospective analysis of 13 culture-proven fungal keratitis cases (2013-2017).
  • Genotyping of fungal isolates and antifungal susceptibility testing were performed.

Main Results:

  • Vegetable matter corneal abrasion was the primary predisposing factor.
  • Fusarium solani and Fusarium dimerum were the most common species.
  • F. solani infections showed higher rates of clinical failure; voriconazole and amphotericin B were most effective.

Conclusions:

  • Fusarium species dominate fungal keratitis in Réunion Island, consistent with tropical patterns.
  • These infections can lead to significant visual impairment, necessitating targeted antifungal strategies.
Keywords:
FusariumKeratitisKératiteRéunion IslandÎle de la Réunion

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