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Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy

Sidra Khalid1, Aariez Khalid2, Hamed Daw3

  • 1Internal Medicine Residency, Fairview Hospital, Cleveland Clinic, USA.

Cureus
|April 25, 2018
PubMed

Primary mediastinal B-cell lymphoma (PMBCL) is a subtype of non-Hodgkin's lymphoma, which occurs rarely in pregnancy. We present a case of a pregnant 22-year-old female who presented with syncope and dyspnea. Computed tomography (CT) chest showed an anterior mediastinal mass, and its biopsy showed PMBCL. Since she was in her second trimester, we decided to treat her with rituximab-cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP). Our case emphasizes the safety of chemotherapy in the second and third trimesters, with good maternal and fetal outcomes.

Keywords:
fetalpmbclpregnancyradiationrchoprice

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