Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Amino acids03:42

Amino acids

106.2K
Amino acids are the monomers that comprise proteins. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha (α) carbon, bonded to an amino group (NH2), a carboxyl group (COOH), and to a hydrogen atom. Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group. There are 20 common amino acids present in proteins, each with a different R group. Variation in the amino acid sequence is responsible for...
106.2K
Polyprotic Acids03:38

Polyprotic Acids

32.1K
Acids are classified by the number of protons per molecule that they can give up in a reaction. Acids such as HCl, HNO3, and HCN that contain one ionizable hydrogen atom in each molecule are called monoprotic acids. Their reactions with water are:
32.1K
Mixtures of Acids03:27

Mixtures of Acids

21.9K
The pH of a solution containing an acid can be determined using its acid dissociation constant and its initial concentration. If a solution contains two different acids, then its pH can be determined using one of several methods depending upon the relative strength of the acids and their dissociation constants.
A Mixture of a Strong Acid and a Weak Acid
In a mixture of a strong acid and a weak acid, the strong acid dissociates completely and becomes a source of almost all the hydronium ions...
21.9K
Nucleic Acids02:43

Nucleic Acids

50.7K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
50.7K
Nucleic acids02:43

Nucleic acids

190.7K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
190.7K
Acidity of Carboxylic Acids01:21

Acidity of Carboxylic Acids

8.7K
Carboxylic acids are the strongest organic acids. However, their acidic strength is much less than mineral acids like HCl. Carboxylic acids ionize in water and readily lose the hydroxyl proton to form a resonance-stabilized carboxylate ion.
8.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The new patterns of nephrolithiasis: What has been changing in the last millennium?

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica·2021
Same author

Urological emergency activities during COVID-19 pandemic: Our experience.

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica·2020
Same author

Changing in gender prevalence of nephrolithiasis.

Urologia·2020
Same author

The impact of potassium citrate therapy in the natural course of Medullary Sponge Kidney with associated nephrolithiasis.

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica·2019
Same author

Metabolic evaluation in patients with infected nephrolithiasis: Is it necessary?

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica·2016
Same author

Urolithiasis in renal transplantation: diagnosis and management.

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica·2015

Related Experiment Video

Updated: Feb 11, 2026

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril
10:02

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Published on: October 3, 2020

4.5K

Uric acid nephrolithiasis: An update.

Elisa Cicerello1

  • 1Unità Complessa di Urologia, Ospedale Ca' Foncello, Treviso, Italy.

Urologia
|April 25, 2018
PubMed
Summary

Uric acid nephrolithiasis is rising, linked to low urinary pH and metabolic issues. Management focuses on urinary pH, volume, and uric acid production to prevent stone formation.

Area of Science:

  • Nephrology
  • Urology
  • Metabolic Medicine

Background:

  • Uric acid nephrolithiasis prevalence is increasing.
  • Low urinary pH is a known risk factor, with recent links to metabolic conditions.
  • Global warming may exacerbate climate risks for stone formation.

Purpose of the Study:

  • To review recent insights into the pathophysiology of uric acid stones.
  • To discuss the management strategies for uric acid nephrolithiasis.

Main Methods:

  • Literature review of recent findings on uric acid stone pathophysiology.
  • Analysis of associations between metabolic conditions and low urinary pH.
  • Examination of therapeutic steps for uric acid stone management.
Keywords:
Uric acid stonesalkalizationallopurinolfebuxostatgouturinary pH

More Related Videos

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications
10:48

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications

Published on: July 28, 2021

4.7K
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.8K

Related Experiment Videos

Last Updated: Feb 11, 2026

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril
10:02

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Published on: October 3, 2020

4.5K
Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications
10:48

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications

Published on: July 28, 2021

4.7K
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.8K

Main Results:

  • Low urinary pH is the primary factor for uric acid precipitation and stone formation.
  • Conditions like diabetes, metabolic syndrome, and dietary factors contribute to low urinary pH.
  • Effective management requires identifying urinary pH profiles, volume status, and disorders of uric acid production.

Conclusions:

  • Understanding the interplay of metabolic factors and urinary pH is crucial for managing uric acid stones.
  • Addressing low urinary pH and associated conditions is key to preventing uric acid nephrolithiasis.
  • A multi-faceted approach to management is necessary for optimal patient outcomes.