Related Experiment Video
Updated: Feb 11, 2026

05:01
A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
Published on: July 1, 2020
3.8K
miRwayDB: a database for experimentally validated microRNA-pathway associations in pathophysiological conditions
Sankha Subhra Das1, Pritam Saha2, Nishant Chakravorty1
1School of Medical Science and Technology, Indian Institute of Technology, Kharagpur, West Bengal, 721302, India.
Database : the Journal of Biological Databases and Curation
|April 25, 2018
Summary
This study introduces a novel database for accessing scientific literature, enhancing research efficiency. It provides a centralized platform for researchers to discover and utilize a vast collection of scientific documents.
Area of Science:
- Computer Science
- Information Science
- Digital Libraries
Background:
- The proliferation of scientific research necessitates efficient methods for information retrieval.
- Existing databases often lack comprehensive coverage or user-friendly interfaces.
- A centralized, searchable repository is crucial for advancing scientific discovery.
Purpose of the Study:
- To develop and present a comprehensive, web-accessible scientific literature database.
- To facilitate seamless access to a wide range of research papers and articles.
- To support researchers by providing a robust tool for literature review and knowledge discovery.
Main Methods:
- The database was constructed by aggregating and indexing a large corpus of scientific documents.
- A web-based interface was developed for intuitive searching and browsing.
- Advanced search algorithms were implemented to ensure accurate and relevant results.
Main Results:
- The database, accessible at http://www.mirway.iitkgp.ac.in, offers extensive coverage of scientific literature.
- User testing confirmed the platform's ease of use and effectiveness in information retrieval.
- The system successfully indexed a significant volume of research papers, providing valuable metadata.
Conclusions:
- The developed database serves as a valuable resource for the scientific community.
- Improved access to scientific literature can accelerate research and innovation.
- This initiative supports the broader goal of open science and knowledge sharing.
Related Concept Videos
MicroRNAs
24.3K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
24.3K
MicroRNAs
4.1K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
4.1K
Reliability and Validity
14.1K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
14.1K
Pathophysiology of Diabetes
3.7K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.7K
Hypertension II: Pathophysiology
1.0K
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
1.0K
Pneumonia II: Pathophysiology
3.1K
The pathophysiology of pneumonia involves the following steps:
3.1K

