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Updated: Feb 11, 2026

Nitropeptide Profiling and Identification Illustrated by Angiotensin II
Published on: June 16, 2019
When All Else Fails: Novel Use of Angiotensin II for Vasodilatory Shock: A Case Report
Jonathan H Chow1, Samuel M Galvagno1, Kenichi A Tanaka2
1From the Department of Anesthesiology, Division of Critical Care Medicine.
Abstract:
Angiotensin (AT) II is an endogenous hormone that acts on venous and arterial smooth muscle to cause vasoconstriction. Recent trials have sparked great interest in its ability to be used as a vasopressor for catecholamine-refractory hypotension. Herein, we describe the successful use of AT II in a patient with a colonic perforation with septic shock refractory to conventional treatment. After AT II initiation, there was an immediate reduction in catecholamine requirement, and the patient survived.
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