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Use of Plant and Herb Derived Medicine for Therapeutic Usage in Cardiology
Ye Eun Koo1, Jiwon Song2, Soochan Bae3
1Beth Israel Deaconess Medical Center, Cardiovascular Institute, 3 Blackfan Circle, CLS 910, Boston, MA 02215, USA. yeeun.koo@tufts.edu.
Insights
Plant- and herb-derived compounds offer a promising alternative for managing cardiovascular diseases (CVDs). These natural remedies help reduce inflammation and oxidative stress, potentially improving heart health with fewer side effects.
Area of Science:
- Cardiovascular Medicine
- Pharmacology
- Natural Product Chemistry
Background:
- Cardiovascular diseases (CVDs) are a leading cause of mortality and morbidity.
- Prevalent conditions like hypertension, atherosclerosis, and oxidative stress are increasing.
- Conventional drugs for CVDs often have adverse effects, necessitating alternative treatments.
Purpose of the Study:
- To review plant- and herb-derived drugs for treating cardiovascular conditions.
- To examine their role in managing inflammation and oxidative stress.
- To explore the potential of combining plant-derived medicines with nanoparticles for targeted therapy.
Main Methods:
- Literature review of scientific studies on plant- and herb-derived compounds for CVDs.
- Analysis of research on natural preventative foods (e.g., grape seed) and therapeutic drugs (e.g., Xanthone).
- Investigation into the synergistic effects of plant compounds and nanoparticles.
Main Results:
- Plant- and herb-derived foods, like grape seed, can inhibit histopathological changes and modulate biomarkers in vital organs.
- Therapeutic agents, such as Xanthone, demonstrate efficacy in improving heart function by reducing myocyte oxidative stress.
- Natural remedies generally exhibit fewer side effects compared to conventional drugs.
Conclusions:
- Plant- and herb-derived medicines are valuable in managing inflammation and oxidative stress associated with CVDs.
- These natural compounds offer a safer alternative or adjunct to conventional CVD treatments.
- Future research directions include exploring nanoparticle-based targeted delivery of plant-derived therapies for enhanced clinical efficacy.
Abstract:
Cardiovascular diseases (CVDs) have become prominent in mortality and morbidity rates. Prevalent cardiovascular conditions, such as hypertension, atherosclerosis and oxidative stress, are increasing at an alarming rate. Conventional drugs have been associated with adverse effects, suggesting a need for an alternative measure to ameliorate CVD. A number of plant- and herb-derived preventative food and therapeutic drugs for cardiovascular conditions are progressively used for their various benefits. Naturally derived food and drugs have fewer side effects because they come from natural elements; preventative food, such as grape seed, inhibits changes of histopathology and biomarkers in vital organs whereas therapeutic drugs, for instance Xanthone, improve heart functions by suppressing oxidative stress of myocyte. This review closely examines the various plant- and herb-derived drugs that have assumed an essential role in treating inflammation and oxidative stress for prevalent cardiovascular conditions. Furthermore, the use of plant-derived medicine with other synthetic particles, such as nanoparticles, for targeted therapy is investigated for its effective clinical use in the future.
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