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Bacterial contamination hypothesis: a new concept in endometriosis

Khaleque N Khan1, Akira Fujishita2, Koichi Hiraki2

  • 1Graduate School of Medical Science Department of Obstetrics and Gynecology Kyoto Prefectural University of Medicine Kyoto Japan.

Reproductive Medicine and Biology
|April 26, 2018
PubMed
Summary

Bacterial contamination, specifically from E. coli in menstrual blood, may drive endometriosis. Intrauterine microbial colonization worsens with GnRH agonist treatment, suggesting new therapeutic targets beyond estrogen suppression.

Keywords:
Toll‐like receptorbacterial endotoxinendometriosisgonadotrophin‐releasing hormone agonistmenstrual blood

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