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Association between obstructive sleep apnea and optic neuropathy: a Taiwanese population-based cohort study
Ming-Hui Sun1, Yaping Joyce Liao2, Che-Chen Lin3,4,5
1Department of Ophthalmology, Chang Gung Memorial Hospital Linkou Medical Center, Chang Gung University, Taoyuan, Taiwan.
Eye (London, England)
|April 27, 2018
Summary
Obstructive sleep apnea (OSA) significantly increases the risk of optic neuropathy (ON). Continuous positive airway pressure (CPAP) treatment for OSA did not appear to reduce this risk in our study.
Area of Science:
- Ophthalmology
- Neurology
- Sleep Medicine
Background:
- Obstructive sleep apnea (OSA) is linked to various systemic diseases like diabetes and hypertension.
- The association between OSA and optic neuropathy (ON) requires further investigation.
Purpose of the Study:
- To examine the relationship between OSA and ON.
- To assess if OSA treatment impacts the risk of developing ON.
Main Methods:
- Utilized data from Taiwan's National Health Insurance program (Longitudinal Health Insurance Database).
- Included one million participants for a large-scale cohort study.
Main Results:
- OSA patients exhibited a 1.95-fold higher risk of ON compared to non-OSA individuals.
- The risk of ON was notably higher in males and individuals under 45 years old.
- Continuous positive airway pressure (CPAP) treatment for OSA did not decrease the risk of ON.
Conclusions:
- OSA is an independent risk factor for developing ON.
- Current evidence suggests CPAP treatment may not mitigate the risk of ON.
- Further research with detailed OSA severity and treatment data is necessary.
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