Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

7.8K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.8K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

5.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.7K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.0K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.0K
Co-activators and Co-repressors02:04

Co-activators and Co-repressors

8.7K
Gene transcription is regulated by the synergistic action of several proteins that form a complex at a gene regulatory site. This is observed in eukaryotes, where the regulation of gene expression is a complex process. Regulatory proteins in eukaryotes can broadly be classified into two types – regulators that bind directly to specific DNA sequences and co-regulators that associate with regulatory proteins but cannot directly bind to the DNA. These co-regulators are further divided into...
8.7K
What are Proteins?01:55

What are Proteins?

240.4K
Overview
240.4K
Social Scripts02:10

Social Scripts

10.3K
People tend to know what behavior is expected of them in specific, familiar settings. A script is a person’s knowledge about the sequence of events expected in a specific setting (Schank & Abelson, 1977). Essentially, scripts are a particular kind of schema, one containing default values for the features within an event. In the restaurant example, the script's features include the props (e.g., tables, menu, food, and money), the roles to be played (e.g., customer and waiter),...
10.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-world outcomes of bispecific antibody therapy after chimeric antigen receptor T-cell therapy in follicular lymphoma.

Blood cancer journal·2026
Same author

Association of Mental Health Disorders with Outcomes after Achilles Tendon Repair: A Propensity-Matched Cohort Study.

Orthopaedic journal of sports medicine·2026
Same author

An Unusual Pattern of Hepatic Involvement in Plasma Cell Leukemia.

Cureus·2026
Same author

Management of hematological toxicities after BCMA-directed CAR-T cell therapy.

Blood cancer journal·2026
Same author

Comparison of All-Inside Suture Implant Versus Suture Hook Technique for Meniscal Ramp Lesions: A Systematic Review and Meta-analysis.

Orthopaedic journal of sports medicine·2026
Same author

Hip Surgical Treatment Registry (HipSTR): The North American Hip Arthroscopy Registry-Who We Are Operating on and What We Are Doing; Findings in Its Inaugural Year 2023 With >1000 Patients.

The American journal of sports medicine·2026

Related Experiment Video

Updated: Feb 11, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.5K

Ectopic thyroid: The great mimicker.

Yazdan Raji1, Supriya Gupta1, Darko Pucar1

  • 1Department of Radiology and Imaging, The Medical College of Georgia at Augusta University, Augusta, Georgia, USA.

Lung India : Official Organ of Indian Chest Society
|April 27, 2018
PubMed
Summary
This summary is machine-generated.

Ectopic thyroid tissue in the mediastinum is rare, often mistaken for malignancy. This report details two cases, highlighting imaging for diagnosis and surgical considerations.

Keywords:
Computed tomographymalignancymediastinal ectopic thyroidpositron emission tomography-computed tomography

More Related Videos

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

2.3K
A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery
04:42

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery

Published on: February 17, 2023

1.8K

Related Experiment Videos

Last Updated: Feb 11, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.5K
Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

2.3K
A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery
04:42

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery

Published on: February 17, 2023

1.8K

Area of Science:

  • Endocrinology
  • Thoracic Surgery
  • Diagnostic Imaging

Background:

  • Ectopic thyroid tissue, though rare, is more common in patients with existing thyroid pathology.
  • It arises from abnormal thyroid gland development during embryonic migration to the pretracheal area.

Observation:

  • Two cases of mediastinal ectopic thyroid tissue initially suspected as malignancies are presented.
  • Diagnostic workup involved computed tomography (CT) and positron emission tomography (PET) scans.

Findings:

  • Imaging characteristics of ectopic thyroid tissue are crucial for differential diagnosis of mediastinal masses.
  • Despite medical treatment options for asymptomatic cases, both patients chose surgical resection.

Implications:

  • Clinicians should consider ectopic thyroid tissue in the differential diagnosis of mediastinal masses.
  • Understanding imaging features aids in accurate diagnosis and patient management decisions.