Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

1.4K
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
1.4K
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

1.0K
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
1.0K
Antimicrobial Proteins01:23

Antimicrobial Proteins

14.5K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
14.5K
Gene Therapy00:59

Gene Therapy

27.7K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.7K
Group Therapy01:26

Group Therapy

460
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
460
Behavior Therapy01:22

Behavior Therapy

732
Behavior therapy incorporates diverse techniques rooted in classical conditioning principles to address maladaptive behaviors and anxiety disorders. These methods aim to reduce avoidance behaviors, foster adaptive coping mechanisms, and alter associations between stimuli and responses, making them effective in a wide range of therapeutic contexts.
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
732

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Pathology-Instructed Theranostic Platform with Mechanoadaptive and ROS-Powered Nanobreathing Functions for Precision Myocardial Repair.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Universal Base-Catalyzed Aza-Michael Addition: A General Platform for Transforming Polyurethanes into High-Performance Injectable Thermogels.

Journal of the American Chemical Society·2026
Same author

Visible Light Photo-Cross-Linked Thermogel─A Single-Component Hybrid Supramolecular-Covalent Hydrogel for Sustained Drug Release.

ACS applied materials & interfaces·2026
Same author

Demethylation of Fluorine-Free Ethers to Reconcile Li<sup>+</sup> Transport Kinetics and Oxidation Stability.

Journal of the American Chemical Society·2026
Same author

Electrocatalytic Properties of Binary PdSn Nanoparticles for Ethanol Oxidation.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Designing MOF-Thermogel Nanocomposites for Differential Multidrug Release in Combination Cancer Therapy.

ACS applied nano materials·2026
Same journal

Development and applications of epitaxial heterostructures based on organic nanowires.

Chemical Society reviews·2026
Same journal

Mechanochemical strategies for environmental remediation and resource recovery.

Chemical Society reviews·2026
Same journal

Shaping perovskite materials into micro/nanostructures for photonics and optoelectronic applications.

Chemical Society reviews·2026
Same journal

Direct air capture technologies: innovations, integration, and pathways to scale.

Chemical Society reviews·2026
Same journal

Fluorescent merocyanines: from fundamental properties to applications as molecular probes, in bioimaging and as emissive dye aggregates.

Chemical Society reviews·2026
Same journal

Direct impure water electrolysis at industrial scale.

Chemical Society reviews·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

18.0K

Supramolecular hydrogels for antimicrobial therapy.

Benhui Hu1, Cally Owh, Pei Lin Chee

  • 1Innovative Center for Flexible Devices (iFLEX), School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. chenxd@ntu.edu.sg.

Chemical Society Reviews
|April 27, 2018
PubMed
Summary
This summary is machine-generated.

Supramolecular hydrogels offer promising solutions for combating drug-resistant microbes in healthcare. These advanced materials can be designed with inherent antimicrobial properties or loaded with therapeutic agents for enhanced infection control.

More Related Videos

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

8.9K
Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

10.5K

Related Experiment Videos

Last Updated: Feb 11, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

18.0K
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

8.9K
Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

10.5K

Area of Science:

  • Biomaterials Science
  • Infectious Diseases
  • Drug Delivery

Background:

  • Drug-resistant microbes pose a significant global health threat.
  • Microbial infections limit the use of essential healthcare materials.
  • Antimicrobial therapy faces challenges due to microbial resistance.

Purpose of the Study:

  • To review and categorize antimicrobial hydrogels for medical applications.
  • To explore strategies for enhancing the antimicrobial efficacy of hydrogels.
  • To highlight the potential of supramolecular hydrogels in combating microbial infections.

Main Methods:

  • Categorization of antimicrobial hydrogels based on inherent properties or encapsulated agents.
  • Discussion of strategies to improve hydrogel antimicrobial performance.
  • Review of supramolecular hydrogel advantages in medical settings.

Main Results:

  • Supramolecular hydrogels exhibit tunable and reversible interactions, ideal for therapeutic agent incorporation.
  • Hydrogels can be designed with intrinsic antimicrobial activity or serve as carriers for antimicrobial compounds.
  • Enhanced efficacy can be achieved through antifouling agents and stimuli-responsive designs.

Conclusions:

  • Supramolecular hydrogels are versatile platforms for developing advanced antimicrobial therapies.
  • These hydrogels offer tunable properties for efficient and safe medical applications.
  • Integration with modern technology can lead to novel antimicrobial systems.