Related Experiment Video
Updated: Feb 11, 2026

Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography
Published on: October 17, 2018
3D printing from microfocus computed tomography (micro-CT) in human specimens: education and future implications.
Susan C Shelmerdine1,2, Ian C Simcock1,2, John Ciaran Hutchinson1,3
11 UCL Great Ormond Street Institute of Child Health , London , UK.
High-resolution micro-CT imaging enables detailed 3D printing of anatomical models. This technique offers new insights for craniofacial surgery, developmental biology, and pathology, advancing medical applications.
Area of Science:
- Biomedical Imaging
- 3D Printing Technology
- Anatomical Modeling
Background:
- Microfocus CT (micro-CT) offers resolution comparable to light microscopy.
- Traditionally used in engineering and preclinical studies, micro-CT is expanding into clinical applications like fetal and pathological imaging.
- Existing 3D printing from medical scans uses lower resolution data.
Purpose of the Study:
- To review the emerging applications of 3D printing from high-resolution micro-CT data.
- To highlight the potential of micro-CT in creating accurate anatomical models.
- To explore diverse fields benefiting from this advanced imaging technique.
Main Methods:
- Utilizing high-resolution micro-CT imaging (voxel sizes <1 micron).
- Processing 3D datasets to generate detailed anatomical models.
- Applying 3D printing to create physical models from micro-CT data.
Main Results:
- Micro-CT enables characterization of smaller structures than conventional CT/MR.
- Generated 3D printed models provide accurate anatomical representations.
- Examples demonstrate applications in craniofacial surgery, cardiac anatomy, placental imaging, archaeology, and bone imaging.
Conclusions:
- 3D printing of micro-CT specimens offers significant potential in various scientific and clinical fields.
- This technique enhances anatomical understanding and provides valuable tools for surgical planning and education.
- Future applications of high-resolution 3D printed models are expected to expand.
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography
Types of Records II: Educational and Administrative Records
Radiological Investigation I: X-ray and CT
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies for Cardiovascular System V: CT

