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Updated: Feb 11, 2026

Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
Published on: August 6, 2014
Molecular biological features of male germ cell differentiation
Hiromitsu Tanaka1, Mika Hirose1, Keizo Tokuhiro1
1TANAKA Project, Center for Advanced Science and Innovation.
Abstract:
Somatic cell differentiation is required throughout the life of a multicellular organism to maintain homeostasis. In contrast, germ cells have only one specific function; to preserve the species by conveying the parental genes to the next generation. Recent studies of the development and molecular biology of the male germ cell have identified many genes, or isoforms, that are specifically expressed in the male germ cell. In the present review, we consider the unique features of male germ cell differentiation. (Reprod Med Biol 2007; 6: 1-9).
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