Commentary Letter to the Editor Regarding Impact of Intrauterine Infusion of Autologous Platelet-Rich Plasma on...

We commend Liang et al. for their rigorous meta-analysis of intrauterine platelet-rich plasma infusion in ART, particularly for recurrent implantation failure, but note issues affecting interpretation. Forest plot axes label "favors control/PRP" using a harm-oriented convention, inverting standard visual interpretation. The methods state a random-effects model, yet reported effect sizes and heterogeneity statistics match fixed-effect estimation, likely narrowing confidence intervals and overstating precision for live birth rate. One figure omits two included studies without explanation, undermining transparency. Non-significant subgroup findings are described as clinically meaningful, risking overinterpretation absent pre-specified hypotheses or multiplicity correction. Accurate, outcome-specific labeling and internally consistent model reporting are essential safeguards against misreading otherwise sound evidence, given its direct bearing on patient counseling and clinical decisions. We encourage a clarifying erratum to preserve this work's scientific integrity and clinical utility.