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Complete Genome Sequence of Multiple-Antibiotic-Resistant Streptococcus parauberis Strain SPOF3K, Isolated from

Yoonhang Lee1, Thanh Luan Nguyen1, Ahran Kim1

  • 1Department of Aquatic Life Medicine, Pukyong National University, Busan, Republic of Korea.

Genome Announcements
|April 28, 2018
PubMed

Insights

We sequenced the genome of antibiotic-resistant Streptococcus parauberis (S. parauberis) strain SPOF3K, found in diseased olive flounder. This provides a complete genetic blueprint for this important fish pathogen.

Area of Science:

  • Microbiology
  • Genomics
  • Aquatic Animal Health

Background:

  • * *Streptococcus parauberis* is a significant pathogen affecting olive flounder.
  • * Antibiotic resistance in fish pathogens poses a threat to aquaculture and food safety.
  • * Understanding the genetic basis of resistance is crucial for disease management.

Purpose of the Study:

  • * To determine the complete genome sequence of a multiple-antibiotic-resistant *Streptococcus parauberis* strain (SPOF3K).
  • * To provide a genomic resource for studying antibiotic resistance mechanisms in this fish pathogen.

Main Methods:

  • * Whole-genome sequencing was performed using the PacBio platform.
  • * Bioinformatic analysis was used to assemble the genome and identify protein-coding genes.

Main Results:

  • * A complete circular chromosome of 2,128,740 base pairs was obtained.
  • * A plasmid of 23,538 base pairs was identified.
  • * The chromosome and plasmid harbor 2,123 and 24 protein-coding genes, respectively.
  • * The strain exhibits multiple-antibiotic resistance.

Conclusions:

  • * The complete genome sequence of *S. parauberis* SPOF3K offers valuable insights into its genetic makeup.
  • * This genomic data can aid in developing strategies to combat antibiotic resistance in aquaculture.
  • * Further research can explore the identified genes for potential virulence and resistance factors.

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