Related Experiment Video
Updated: Feb 11, 2026

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
Published on: April 26, 2015
Effective ventilation: The most critical intervention for successful delivery room resuscitation
Elizabeth E Foglia1, Arjan B Te Pas2
1Division of Neonatology, The Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Insights
Effective positive pressure ventilation is crucial for neonatal resuscitation, supporting the critical transition from fetal to newborn cardiopulmonary physiology. This review covers ventilation strategies for delivery room care.
Area of Science:
- Neonatal Physiology
- Cardiopulmonary Transition
- Resuscitation Science
Background:
- Lung aeration initiates the shift from fetal to postnatal circulation.
- Apnea or inadequate breathing in newborns necessitates immediate intervention.
- Positive pressure ventilation is fundamental to neonatal resuscitation.
Purpose of the Study:
- To review the physiology of cardiopulmonary transition at birth.
- To highlight key factors for effective ventilation during neonatal resuscitation.
- To summarize clinical evidence on ventilation strategies in the delivery room.
Main Methods:
- Review of physiological principles of cardiopulmonary transition.
- Analysis of clinical evidence for neonatal resuscitation strategies.
- Focus on positive pressure ventilation techniques and monitoring.
Main Results:
- Understanding cardiopulmonary transition is key to effective resuscitation.
- Caregiver considerations are vital for successful ventilation.
- Evidence supports specific strategies for delivery room ventilation.
Conclusions:
- Effective positive pressure ventilation is essential for neonatal survival.
- Optimizing ventilation techniques improves cardiopulmonary transition outcomes.
- Further research on delivery room ventilation strategies is warranted.
Abstract:
Lung aeration is the critical first step that triggers the transition from fetal to postnatal cardiopulmonary physiology after birth. When an infant is apneic or does not breathe sufficiently, intervention is needed to support this transition. Effective ventilation is therefore the cornerstone of neonatal resuscitation. In this article, we review the physiology of cardiopulmonary transition at birth, with particular attention to factors the caregiver should consider when providing ventilation. We then summarize the available clinical evidence for strategies to monitor and perform positive pressure ventilation in the delivery room setting.
More Related Videos
Related Concept Videos
Ecological Succession
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Cardiopulmonary Resuscitation I: Adult
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Nursing Interventions I: Taxonomy of Nursing Interventions
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions

