Related Experiment Video

Updated: Feb 11, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.7K

Role of Coronary Flow Velocity in Predicting Adverse Outcome in Clinical Practice

Angela Zagatina1, Nadezhda Zhuravskaya1, Maxim Kamenskikh2

  • 1Medika Cardiocenter, Saint Petersburg, Russian Federation.

Ultrasound in Medicine & Biology
|May 1, 2018
PubMed

Insights

High local velocity in coronary arteries detected by echocardiography predicts adverse cardiac events. This finding offers a new prognostic tool for patients, improving risk assessment and guiding clinical decisions.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Echocardiography

Background:

  • Prognostic value of local high velocity in coronary arteries via echocardiography is not well-established.
  • Echocardiography is a key non-invasive imaging modality in cardiovascular diagnostics.

Purpose of the Study:

  • To determine the prognostic significance of local coronary artery velocity exceeding 70 cm/s.
  • To evaluate this velocity as a predictor of major adverse cardiac events (MACEs).

Main Methods:

  • Prospective study involving 412 patients.
  • Coronary arteries (left main, anterior, circumflex) assessed for local velocity >70 cm/s using echocardiography.
  • Major adverse cardiac events (MACEs) defined as death, non-fatal myocardial infarction, acute pulmonary edema, acute coronary syndrome, and revascularization.

Main Results:

  • A significant association was found between high local velocity and increased incidence of death (6.4% vs. 0%), acute cardiac events (10% vs. 0%), and MACEs (62% vs. 0%).
  • Maximal local velocity independently predicted death (OR=1.02) and MACEs (OR=1.04).
  • Successful visualization of coronary artery segments was achieved in 91% of cases.

Conclusions:

  • Local high velocity (>70 cm/s) in coronary arteries during echocardiography is a significant independent predictor of adverse cardiac outcomes.
  • Echocardiographic assessment of local coronary artery velocity may enhance prognostic stratification in cardiovascular patients.

Keywords:
Coronary DopplerCoronary artery flow velocityCoronary stenosesPrognosis coronary flowPrognosis echoTransthoracic echo

More Related Videos

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

15.7K
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

5.9K

Related Concept Videos

Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
11.0K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
447
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
411
Velocity and Acceleration in Steady and Unsteady Flow01:11

Velocity and Acceleration in Steady and Unsteady Flow

In fluid mechanics, velocity and acceleration are key concepts for analyzing particle motion in both steady and unsteady flow. Consider a fluid particle moving along a pathline, where its velocity depends on its position and time. The particle's acceleration is obtained by differentiating the velocity with respect to time.
The acceleration can be generalized to any point in the flow, and expressed as components along three perpendicular directions, representing changes in velocity over...
419
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries
46.1K
Outcomes of Glycolysis01:13

Outcomes of Glycolysis

Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
107.6K