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Candida auris: Disinfectants and Implications for Infection Control
Tsun S N Ku1,2, Carla J Walraven3, Samuel A Lee1,2
1Section of Infectious Disease, New Mexico VA Health Care System, Albuquerque, NM, United States.
Frontiers in Microbiology
|May 1, 2018
Summary
Candida auris infections are a growing threat due to multidrug resistance and frequent misidentification. Chlorine-based disinfectants show the most promise for environmental decontamination against this emerging pathogen.
Area of Science:
- * Infectious Diseases
- * Microbiology
- * Infection Control
Background:
- * Candida auris is an emerging multidrug-resistant fungal pathogen causing severe, high-mortality infections.
- * It is often misidentified by standard clinical laboratory techniques, necessitating specialized identification methods.
- * Nosocomial transmission and outbreaks are documented, highlighting the need for effective control measures.
Purpose of the Study:
- * To review the available data on the efficacy of disinfectants and antiseptics against Candida auris.
- * To identify optimal strategies for environmental surface disinfection and patient decolonization.
- * To guide infection control practices in healthcare settings.
Main Methods:
- * Review of existing literature on disinfectant and antiseptic effectiveness against Candida auris.
- * Analysis of in vitro studies and clinical reports on decontamination and hand hygiene.
- * Evaluation of chlorine-based products, adjunctive disinfectants, and antiseptics like chlorhexidine gluconate.
Main Results:
- * Chlorine-based disinfectants demonstrate the highest efficacy for environmental surface disinfection against Candida auris.
- * Other disinfectants may serve as adjunctive agents, but a comprehensive cleaning protocol is essential.
- * Antiseptic efficacy, including chlorhexidine gluconate, for patient decolonization and healthcare worker hand hygiene is variable, with persistent colonization reported.
Conclusions:
- * Effective control of Candida auris requires robust infection control measures, including appropriate disinfection and cleaning protocols.
- * Chlorine-based disinfectants are recommended for environmental decontamination.
- * Further research is needed to validate disinfectants and antiseptics for real-world application, especially for hand hygiene and patient decolonization.
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