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Overview of Advanced Functional Groups

Overview of Advanced Functional Groups

Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
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Related Experiment Video

Updated: Feb 11, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

Recent Advances in Polyanhydride Based Biomaterials.

Arijit Basu^1,2, Abraham J Domb¹

¹School of Pharmacy - Faculty of Medicine, The Hebrew University of Jerusalem, Hadassah Ein Kerem Medical Center Campus, Jerusalem, 91120, Israel.

Advanced Materials (Deerfield Beach, Fla.)

|May 1, 2018

Summary

This summary is machine-generated.

Recent advancements in polyanhydride chemistry have led to degradable synthetic biopolymers with extended shelf-life, improving drug delivery systems. These materials show promise in biomedical electronics and vaccine delivery.

Keywords:

alternating polyanhydride bioelectronics melt condensation poly(ester-anhydride)polyanhydride vaccine delivery

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Area of Science:

Polymer Chemistry
Biomaterials Science

Background:

Polyanhydrides are degradable synthetic biopolymers utilized as carriers for controlled drug delivery.
A specific polyanhydride copolymer is used in Gliadel brain tumor implants for carmustine delivery.

Purpose of the Study:

To review recent developments in polyanhydride synthesis and biomedical applications.
To highlight innovations addressing challenges like short shelf-life.

Main Methods:

Review of polyanhydride synthesis approaches.
Examination of recent advancements in biomedical applications.

Main Results:

Discovery of alternating copolymers with extended shelf-life.
Applications in biomedical electronics, vaccine delivery, and nano/micro particulate systems.

Conclusions:

Polyanhydrides offer a versatile platform for drug delivery and other biomedical applications.
Ongoing research focuses on improving stability and expanding their use in advanced systems.