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Updated: Feb 11, 2026

Generation and Recovery of β-cell Spheroids From Step-growth PEG-peptide Hydrogels
Published on: December 6, 2012
Pleated Sheets and Turns of β-Peptides with Proteinogenic Side Chains
Dieter Seebach1, Stefan Abele1, Karl Gademann1
1Laboratorium für Organische Chemie der Eidgenössischen Technischen Hochschule, ETH-Zentrum, Universitätstrasse 16, CH-8092 Zürich (Switzerland), Fax: (+41) 1-632-11-44.
Abstract:
Components of a toolbox with predictable secondary structural elements: β-peptides. The β-peptide shown here with proteinogenic side chains adopts a parallel pleated sheet structure in the solid state upon incorporation of suitably configured β-amino acids. When a β-dipeptide turn segment is incorporated in the center, a hairpin is formed in solution.
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